PEPFAR is accelerating progress toward controlling the AIDS epidemic. The program has strengthened the ability of countries with sizable HIV/AIDS burdens to swiftly address other outbreaks, such as Ebola, avian flu, and cholera, ultimately enhancing global health security and protecting America’s borders.

"My cheeks are sore from smiling," says Loyce Maturu. The 24-year-old, who lives in Harare, Zimbabwe, is posing for a photo at NPR headquarters in Washington, D.C. She's come to be interviewed about her activism. She's a champion for people with HIV/AIDS and TB (she's been diagnosed with both). So really, the pain of smiling is nothing compared to what she's been through.